News & Updates

HDR opportunities

Are you looking for an Honours, Masters, or PhD project in Single Cell or Spatial-Omics? We are seeking talented individuals to join our group. We can tailor projects to suit your interests and desired skill-set. Some project ideas:

Combined gene expression profiling and mutant genotyping of cancer cell lines

We recently developed the snPATHO-seq protocol for gene expression profiling of tissue from Formalin-Fixed, Paraffin-Embedded (FFPE) clinical histology samples. We are looking to expand this probed-based method to identify cancer mutations, allowing users to generate two disparate but crucial datasets from the one simple and cost-effective assay. This has significant benefits both for patient outcomes as well as research applications looking at cancer heterogeneity and their cell signalling and pathway response. The ability to process FFPE samples is important as it enables researchers to access the millions of preserved historical samples across the world's clinical archives. This project would be suitable for an Honours or Masters student looking to complete a combined wet-lab and bioinformatics project.